Craig, D. Q. M.; Royall, P. G.; Reading, M.; Price, D. M.; Lever, T. J.; Furry, J. W.; Micro-thermal analysis for the characterisation of pharmaceutical materials. Proc. 26th NATAS, September 13-15 (1998) Cleveland, Ohio, USA, pp. 610-615
The use of micro-thermal analysis as a novel means of characterising compacted pharmaceutical materials is described, using ibuprofen compacts as model systems. The surface topography, thermal image, heat flow on temperature scanning and temperature-dependent z-axis probe deflection are described, with the implications for the characterisation of pharmaceutical materials outlined.